Pd nanoparticles decorated poly-methyldopa@GO/FeO nanocomposite modified glassy carbon electrode as a new electrochemical sensor for simultaneous determination of acetaminophen and phenylephrine.

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ID: 54366
2019
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Ranked #37 of 133 articles by views in materials science & engineering c, materials for biological applications

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Abstract
In this study, a new nanocomposite consists of magnetic graphene oxide (GO/FeO), poly-methyldopa (PMDA) and Pd nanoparticle was prepared and utilized for constructing an electrochemical sensor to determine acetaminophen (AC) and phenylephrine (PHE). The structure of nanocomposite has been characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDX). The effects of various parameters with effective on the sensor response are optimized. In a range, 5 nM to 2.5 μM for AC and 50 nM to 3 μM for PHE the designed sensor had a response linearly reliant on the AC and PHE concentration respectively by differential pulse voltammetry. Also, the limits of detection for AC and PHE with this sensor were 2.1 nM and 7.8 nM, respectively. It successfully employed for the determination of trace amounts of the AC and PHE in pharmaceutical combination and human serum samples.
Reference Key
lotfi2019pdmaterials Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lotfi, Shahram;Veisi, Hojat;
Journal materials science & engineering c, materials for biological applications
Year 2019
DOI
S0928-4931(19)32150-2
URL
Keywords
electrochemical sensor nanocomposite acetaminophen magnetic graphene oxide phenylephrine

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