Gas-Mediated Cancer Bioimaging and Therapy.

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ID: 51078
2019
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Abstract
Gas-involving cancer theranostics have attracted considerable attention in recent years due to their high therapeutic efficacy and biosafety. We have reviewed the recent significant advances in the development of stimuli-responsive gas releasing molecules (GRMs) and gas nanogenerators for cancer bio-imaging, targeted and controlled gas therapy, and gas-sensitized synergistic therapy. We have focused on gases with known anti-cancer effects, such as oxygen (O2), carbon monoxide (CO), nitric oxide (NO), hydrogen sulfide (H2S), hydrogen (H2), sulfur dioxide (SO2), carbon dioxide (CO2) and heavy gases that act via the gas-generating process. The GRMs and gas nanogenerators for each gas have been described in terms of the stimulation method, followed by their applications in ultrasound and multimodal imaging, and finally their primary and synergistic actions with other cancer therapeutic modalities. The current challenges and future possibilities of gas therapy and imaging vis clinical translation have also been discussed.
Reference Key
chen2019gasmediatedacs Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Chen, Lichan;Zhou, Shu-Feng;Su, Lichao;Song, Jibin;
Journal acs nano
Year 2019
DOI
10.1021/acsnano.9b04954
URL
Keywords Keywords not found

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