Gut microbiota modulation with traditional Chinese medicine: a system biology-driven approach.

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ID: 50621
2019
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Abstract
With the development of system biology, traditional Chinese medicine (TCM) is drawing more and more attention nowadays. However, there are still many enigmas behind this ancient medical system because of the arcane theory and complex mechanism of actions. In recent decades, advancements in genome sequencing technologies, bioinformatics and culturomics have led to the groundbreaking characterization of the gut microbiota, a 'forgotten organ', and its role in host health and disease. Notably, gut microbiota has been emerging as a new avenue to understanding TCM. In this review, we will focus on the structure, composition, functionality and metabolites of gut microbiota affected by TCM so as to conversely understand its theory and mechanisms. We will also discuss the potential areas of gut microbiota for exploring Chinese material medica waste, Chinese marine material medica, add-on therapy and personalized precise medication of TCM. The review will conclude with future perspectives and challenges of gut microbiota in TCM intervention.
Reference Key
yue2019gutpharmacological Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yue, Shi-Jun;Wang, Wen-Xiao;Chen, Yan-Yan;Shi, Xu-Qin;Yan, Dan;Yu, Jin-Gao;Zhou, Gui-Sheng;Jiang, Dong-Jing;Zhang, Li;Wang, Chang-Yun;Duan, Jin-Ao;Tang, Yu-Ping;
Journal pharmacological research
Year 2019
DOI
S1043-6618(19)30661-9
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