Copper-Catalyzed Three-Component Reaction of Alkynes, TMSN, and Ethers: Regiocontrollable Synthesis of N- and N-Oxyalkylated 1,2,3-Triazoles.

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ID: 50531
2019
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Abstract
A new copper-catalyzed selective synthesis of N- and N-oxyalkylated 1,2,3-triazoles has been developed through a three-component reaction of alkynes, TMSN, and ethers. Through this methodology, a series of N- and N-oxyalkylated 1,2,3-triazoles could be efficiently and regioselectively obtained from simple and readily available starting materials with favorable functional group tolerance.
Reference Key
bao2019coppercatalyzedorganic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Bao, Pengli;Yue, Huilan;Meng, Na;Zhao, Xiaohui;Li, Jiangsheng;Wei, Wei;
Journal Organic letters
Year 2019
DOI
10.1021/acs.orglett.9b02295
URL
Keywords
2 1 Docking Triazole DFT qsar 3]triazolo[4 5-d]pyrimidine analogues pyrimidine

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