Isolation and Identification of Secondary Metabolites from the Aerial Parts of Vahl.

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ID: 4850
2017
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Abstract
Vahl is an herbaceous wild plant native to Iran which is traditionally used in Iranian folk medicine as a mild sedative tea for reducing anxiety and for treatment of gastrointestinal disorders. Our previous study on ethyl acetate extract of proved anti-anxiolytic activity and so the present study was designed to determine chemical components of this biologically active fraction. The extract was prepared using maceration method. Column chromatography and medium pressure liquid chromatography (MPLC) was used respectively to separate the fractions. Finally, some evaluated fractions were used for high pressure liquid (HPLC) and peak shaving recycle technique to achieve more purification. Separated compounds were determined using NMR analysis and mass spectroscopy. Six compounds have been isolated from ethylacetate extract of aerial parts of including four flavonoids (apigenin, kumatakenin, penduletin and 4', 7-dihyroxy- 3, 5, 6-trimethoxy flavon), a labdan diterpenoid (labda-13-en-8, 15-diol), and an iridoid.
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sajjadi2017isolationiranian Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sajjadi, Seyed Ebrahim;Ghanadian, Seyed Mustafa;Rabbani, Mohammad;Tahmasbi, Fateme;
Journal iranian journal of pharmaceutical research
Year 2017
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