Energy-efficiency of Cardiomyocyte Stimulation with Rectangular Pulses.

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ID: 47963
2019
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Abstract
In cardiac pacemaker design, energy expenditure is an important issue. This work aims to explore whether varying stimulation pulse configuration is a viable optimization strategy for reducing energy consumption by the pacemaker. A single cardiomyocyte was used as an experimental model. Each cardiomyocyte was stimulated with different stimulation protocols using rectangular waveforms applied in varying number, in short succession. The amplitude, the width of each pulse, and the interval between consecutive pulses were modified. The application of multiple pulses in a short sequence led to a reduction of the threshold voltage required for stimulation when compared to a single pulse. However, none of the employed multi-pulse sequences reduced the overall energy expenditure of cell stimulation when compared to a single pulse stimulation. Among multiple pulse protocols, a combination of two short pulses (1 ms) separated with a short interval (0.5 ms) had the same energy requirements as a single short pulse (1 ms), but required the application of significantly less voltage. While increasing the number of consecutive pulses does not reduce the energy requirements of the pacemaker, the reduction in threshold voltage can be considered in practice if lower stimulation voltages are desired.
Reference Key
laasmaa2019energyefficiencyscientific Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Laasmaa, Martin;Lu, Pengfei;Veletić, Mladen;Louch, William E;Bergsland, Jacob;Balasingham, Ilangko;Vendelin, Marko;
Journal Scientific reports
Year 2019
DOI
10.1038/s41598-019-49791-w
URL
Keywords
health care Wireless sensor networks Internet of Things authenticity cloud computing cryptography patient monitoring protocols computational cost doctors accurate operations computationally efficient mutual authentication protocol continuous operations cryptographic protocols existing protocol healthcare monitoring system incubator monitoring systems message authentication public key cryptography received information remote healthcare monitoring remote infant incubator monitoring system resource-limited sensors telecommunication security wireless medical sensor networks

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