The 5'-3' distance of RNA secondary structures.

Clicks: 475
ID: 47844
2012
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Abstract
Recently, Yoffe and colleagues observed that the average distances between 5'-3' ends of RNA molecules are very small and largely independent of sequence length. This observation is based on numerical computations as well as theoretical arguments maximizing certain entropy functionals. In this article, we compute the exact distribution of 5'-3' distances of RNA secondary structures for any finite n. Furthermore, we compute the limit distribution and show that for n = 30 the exact distribution and the limit distribution are very close. Our results show that the distances of random RNA secondary structures are distinctively lower than those of minimum free energy structures of random RNA sequences.
Reference Key
han2012thejournal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Han, Hillary S W;Reidys, Christian M;
Journal Journal of computational biology : a journal of computational molecular cell biology
Year 2012
DOI
10.1089/cmb.2011.0301
URL
Keywords
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