Implications of Necroptosis for Cardiovascular Diseases.

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ID: 47616
2019
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Abstract
Necroptosis is a non-apoptotic programmed cell death pathway, which causes necrosis-like morphologic changes and triggers inflammation in the surrounding tissues. Accumulating evidence has demonstrated that necroptosis is involved in a number of pathological processes that lead to cardiovascular diseases. However, the exact molecular pathways linking them remain unknown. Herein, this review summarizes the necroptosis-related pathways involved in the development of various cardiovascular diseases, including atherosclerosis, cardiac ischemia-reperfusion injury, cardiac hypertrophy, dilated cardiomyopathy and myocardial infarction, and may shed light on the diagnosis and treatment of these diseases.
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ruan2019implicationscurrent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ruan, Zhao-Hui;Xu, Zi-Xuan;Zhou, Xue-Yun;Zhang, Xian;Shang, Lei;
Journal current medical science
Year 2019
DOI
10.1007/s11596-019-2067-6
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