Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

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ID: 4741
1970
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Abstract
Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. The presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antipsychotic CDPPB, the anti-obesity drug rimonabant, difenamizole, an analgesic, betazole, a H2-receptor agonist and the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Owing to this diversity in the biological field, this nucleus has attracted the attention of many researchers to study its skeleton chemically and biologically. This review highlights the different synthesis methods and the pharmacological properties of pyrazole derivatives. Studies on the synthesis and biological activity of pyrazole derivatives developed by many scientists around the globe are reported.
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khalid1970synthesismolecules Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Khalid Karrouchi;Smaail Radi;Youssef Ramli;Jamal Taoufik;Yahia N. Mabkhot;Faiz A. Al-aizari;M’hammed Ansar;Karrouchi, Khalid;Radi, Smaail;Ramli, Youssef;Taoufik, Jamal;Mabkhot, Yahia N.;Al-aizari, Faiz A.;Ansar, M’hammed and
Journal molecules
Year 1970
DOI
10.3390/molecules23010134
URL
Keywords Keywords not found

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