You can dance if you want to: A case of Sydenham's chorea.

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ID: 44514
2019
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Ranked #2 of 10 articles by views in The American journal of emergency medicine

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Abstract
Isolated motor disturbances in the paediatric population are uncommon presentations to the emergency department. Choreiform movements have a broad differential diagnosis and may present insidiously with progressive worsening of asymmetric clumsiness, hypotonia and dysarthria. The incidence of Sydenham's chorea (SC) caused by acute rheumatic fever (ARF) is very rare in developed countries. We report a previously healthy, vaccinated 9-year old male who presented to our ED with intermittent and progressive right sided clumsiness for four weeks. Physical examination findings showed dysdiadokinesis and dysmetric movements of the right side, which varied in intensity and were less pronounced on serial re-examination during the same ED visit. Basic bloodwork, MRI and MRA/V showed no abnormalities, and the patient was discharged home with urgent neurology follow-up. He re-presented to our ED four days later with worsening gait and inability to hold a pencil at school. He was subsequently diagnosed with chorea by the neurology team. The cause of chorea was later determined to be SC, and the patient's throat swab came back positive for group A-beta hemolytic strep (GAS) infection. We explore current literature regarding the various presentations of ARF, differential considerations in acute chorea, and diagnostic studies needed to determine the etiology of acute chorea. With the low incidence of chorea in developed nations, this diagnosis can be easily overlooked. We highlight the importance of this diagnosis, as well as primary and secondary treatment in ARF.
儿童孤立性运动障碍在急诊科较为罕见。舞蹈样动作的鉴别诊断范围广泛,且常隐匿起病,表现为不对称性肢体笨拙、肌张力减退和构音障碍的进行性加重。在发达国家,由急性风湿热(ARF)引起的西德纳姆舞蹈病(SC)发病率极低。本文报道了一例既往体健、按计划接种疫苗的9岁男童,因右侧肢体间歇性且进行性笨拙4周就诊于急诊科。体格检查显示右侧轮替运动障碍和辨距不良,其严重程度呈波动性,且在同次急诊就诊的多次复查中有所减轻。基础血液检查、MRI及MRA/V均未见异常,患儿出院并安排神经科紧急随访。4天后,患儿因步态恶化及在校无法握笔而再次就诊于急诊科。随后神经科团队确诊其为舞蹈病。该舞蹈病的病因随后被确定为SC,且患儿咽拭子A组β溶血性链球菌(GAS)检测呈阳性。我们结合现有文献,探讨了ARF的多种临床表现、急性舞蹈病的鉴别考量以及明确急性舞蹈病病因所需的诊断性检查。鉴于发达国家舞蹈病发病率较低,该诊断极易被忽视。我们强调了此项诊断以及ARF一级和二级治疗的重要性。
Reference Key
lubberdink2019youthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lubberdink, Ashley L;Sharif, Sameer;Pardhan, Kaif;
Journal The American journal of emergency medicine
Year 2019
DOI
S0735-6757(19)30551-0
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