Graphene FET array biosensor based on ssDNA aptamer for ultrasensitive Hg 2+ detection in environmental pollutants
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ID: 44496
2018
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Abstract
Invisible mercury ion is an extremely poisonous environmental pollutant, therefore, a fast and highly sensitive detection method is of significant importance. In this study, a liquid-gated graphene field-effect transistor (GFET) array biosensor (6 × 6 GFETs on the chip) was fabricated and applied for Hg2+ quantitate detection based on single-stranded DNA (ssDNA) aptamer. The biosensor showed outstanding selectivity to Hg2+ in mixed solutions containing various metal ions. Moreover, the sensing capability of the biosensor was demonstrated by real-time responses and showed a fairly low detection limit of 40 pM, a wide detection ranged from 100 pM to 100 nM and rapid response time below one second. These results suggest that the GFET array biosensor based on ssDNA aptamer offers a simple fabrication procedure and quite fast method for mercury ion contaminant detection and are promising for various analytical applications.
| Reference Key |
tu2018graphenefrontiers
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|---|---|
| Authors | Tu, J. |
| Journal | Frontiers in chemistry |
| Year | 2018 |
| DOI |
10.3389/fchem.2018.00333
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| URL | |
| Keywords | Keywords not found |
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