Graphene FET array biosensor based on ssDNA aptamer for ultrasensitive Hg 2+ detection in environmental pollutants

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ID: 44496
2018
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Ranked #182 of 234 articles by views in Frontiers in chemistry

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Abstract
Invisible mercury ion is an extremely poisonous environmental pollutant, therefore, a fast and highly sensitive detection method is of significant importance. In this study, a liquid-gated graphene field-effect transistor (GFET) array biosensor (6 × 6 GFETs on the chip) was fabricated and applied for Hg2+ quantitate detection based on single-stranded DNA (ssDNA) aptamer. The biosensor showed outstanding selectivity to Hg2+ in mixed solutions containing various metal ions. Moreover, the sensing capability of the biosensor was demonstrated by real-time responses and showed a fairly low detection limit of 40 pM, a wide detection ranged from 100 pM to 100 nM and rapid response time below one second. These results suggest that the GFET array biosensor based on ssDNA aptamer offers a simple fabrication procedure and quite fast method for mercury ion contaminant detection and are promising for various analytical applications.
Reference Key
tu2018graphenefrontiers Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tu, J.
Journal Frontiers in chemistry
Year 2018
DOI
10.3389/fchem.2018.00333
URL
Keywords Keywords not found

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