Catalyst-free [4 + 2] cyclization of para-quinone methide derivatives with homophthalic anhydrides.
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2018
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Abstract
The title reaction has been established, which offers a useful method for the construction of dihydrocoumarin frameworks in generally good chemical yields (up to 99%) and high diastereoselectivities (up to >95 : 5 dr). This reaction represents a good example of [4 + 2] cyclizations of para-quinone methide derivatives with electron-rich reaction partners under catalyst-free conditions.
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zhou2018catalystfreeorganic
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| Authors | Zhou, Jia-Yu;Ma, Chun;Zhang, Yi-Zhu;Wu, Qiong;Shi, Feng; |
| Journal | Organic & biomolecular chemistry |
| Year | 2018 |
| DOI |
10.1039/c8ob02776e
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