Tyrosinase Inhibition Antioxidant Effect andCytotoxicityStudies of the Extracts of Cudrania tricuspidataFruit Standardized in Chlorogenic Acid.

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ID: 43076
2019
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Abstract
In the present study, various extracts of . tricuspidata fruit were prepared with varying ethanol contents and evaluated for their biomarker and biological properties. The 80% ethanolic extract showed the best tyrosinase inhibitory activity, while the 100% ethanolic extract showed the best total phenolics and flavonoids contents. The HPLC method was applied to analyze the chlorogenic acid in . tricuspidata fruit extracts. The results suggest that the observed antioxidant and tyrosinase inhibitory activity of . tricuspidata fruit extract could partially be attributed to the presence of marker compounds in the extract. In this study, we present an analytical method for standardization and optimization of C. tricuspidata fruit preparations. Further investigations are warranted to confirm the in vivo pharmacological activity of . tricuspidata fruit extract and its active constituents and assess the safe use of the plant for the potential development of the extract as a skin depigmentation agent.
Reference Key
oh2019tyrosinasemolecules Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Oh, Ha-Na;Park, Dae-Hun;Park, Ji-Yeon;Song, Seung-Yub;Lee, Sung-Ho;Yoon, Goo;Moon, Hong-Seop;Oh, Deuk-Sil;Rhee, Sang-Hoon;Im, Eun-Ok;Yoon, In-Soo;Shim, Jung-Hyun;Cho, And Seung-Sik;
Journal molecules
Year 2019
DOI
E3266
URL
Keywords
HPLC tyrosinase c.tricuspidata bureau

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