Switching Tenofovir/Emtricitabine/Efavirenz (TDF/FTC/EFV) to TDF/FTC/Rilpivirine vs Continuing TDF/FTC/EFV in HIV-Infected Patients With Virological Suppression: A Randomized Controlled Trial.
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2019
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Abstract
A randomized controlled noninferiority trial was conducted in HIV-infected patients receiving tenofovir/emtricitabine/efavirenz (TDF/FTC/EFV) with virological suppression in a resource-limited setting. Switching to TDF/FTC/rilpivirine was noninferior to continuing TDF/FTC/EFV in terms of maintaining compete viral suppression at 24 weeks and provided better lipid profiles and fewer central nervous system adverse effects.
| Reference Key |
wiriyatanakorn2019switchingopen
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|---|---|
| Authors | Wiriyatanakorn, Sirichai;Sungkanuparph, Somnuek; |
| Journal | Open forum infectious diseases |
| Year | 2019 |
| DOI |
10.1093/ofid/ofz297
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