The chemistry of isatins: a review from 1975 to 1999

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2001
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Abstract
Isatins (1H-indole-2,3-dione) are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds, such as indoles and quinolines, and as raw material for drug synthesis. Isatins have also been found in mammalian tissue and their function as a modulator of biochemical processes has been the subject of several discussions. The advances in the use of isatins for organic synthesis during the last twenty-five years, as well as a survey of its biological and pharmacological properties are reported in this review and in the accompanying supplementary information.
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Authors da, Silva Joaquim F. M.;J., Garden Simon;C., Pinto Angelo;
Journal journal of the brazilian chemical society
Year 2001
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