Does Metastatic Lymph Node SUVmax Predict Survival in Patients with Esophageal Cancer?

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ID: 4200
2015
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Abstract
We aimed to investigate the SUVmax of primary tumor and metastatic lymph node in predicting survival in patients with esophageal cancer.We retrospectively analyzed patients with esophageal cancer between 2009 and 2011 who had FDG positron-emission tomography (PET)/computed tomography (CT). All patients were followed-up to 2013. Clinical staging, SUVmax of primary tumor and metastatic lymph node were evaluated.One hundred seven patients were included in the study. All patients were followed-up between 2 and 49 months. The mean SUVmax of primary tumor and metastatic lymph node were 19.3±8.8 and 10.4±9.1, respectively. Metastatic lymph node SUVmax had an effect in predicting survival whereas primary tumor SUVmax did not have an effect (p=0.014 and p=0.262, respectively). Multivariate Cox regression analysis showed that clinical stage of the disease was the only independent factor predicting survival (p=0.001).Among patients with esophageal cancer, the value of primary tumor SUVmax did not have an effect on survival. Clinical stage assessed with FDG PET/CT imaging was found to predict survival in esophageal carcinoma. Additionally, lymph node SUVmax was identified as a new parameter in predicting survival in the present study.
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vatankulu2015doesmolecular Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Vatankulu, Betül;Şanlı, Yasemin;Kaytan Sağlam, Esra;Kuyumcu, Serkan;Özkan, Zeynep Gözde;Yılmaz, Ebru;Purisa, Sevim;Adalet, Işık;
Journal molecular imaging and radionuclide therapy
Year 2015
DOI
10.4274/mirt.36744
URL
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