High performance of rapid influenza diagnostic test and variable effectiveness of influenza vaccines in Mexico.

Clicks: 293
ID: 40483
2019
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #31 of 68 articles by views in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
To evaluate the performance of a rapid influenza diagnostic tests (RIDT) and influenza vaccines' effectiveness (VE) during an outbreak setting.We compared the performance of a RIDT with RT-PCR for influenza virus detection in influenza-like illness (ILI) patients enrolled during the 2016/17 season in Mexico City. Using the test-negative design, we estimated influenza VE in all participants and stratified by age, virus subtype, and vaccine type (trivalent vs quadrivalent inactivated vaccines). The protective value of some clinical variables was evaluated by regression analyses.We enrolled 592 patients. RT-PCR detected 93 cases of influenza A(H1N1)pdm09, 55 of AH3N2, 141 of B, and 13 A/B virus infections. RIDT showed 90.7% sensitivity and 95.7% specificity for influenza A virus detection, and 91.5% sensitivity and 95.3% specificity for influenza B virus detection. Overall VE was 33.2% (95% CI: 3.0 - 54.0; p = 0.02) against any laboratory-confirmed influenza infection. VE estimates against influenza B were higher for the quadrivalent vaccine. Immunization and occupational exposure were protective factors against influenza.The RIDT was useful to detect influenza cases during an outbreak setting. Effectiveness of 2016/17 influenza vaccines administered in Mexico was low but significant. Our data should be considered for future local epidemiological policies.
Reference Key
castillejos2019highinternational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Castillejos, Manuel;Cabello-Gutiérrez, Carlos;Choreño-Parra, José Alberto;Hernández, Víctor;Romo, Javier;Hernández-Sánchez, Fernando;Martínez, Dina;Hernández, Andrés;Jiménez-Álvarez, Luis;Hernández-Cardenas, Carmen M;Becerril-Vargas, Eduardo;Martínez-Orozco, José A;Sandoval-Gutiérrez, José Luis;Guadarrama, Cristóbal;Olvera-Masetto, Enrique;Alfaro-Ramos, Leticia;Cruz-Lagunas, Alfredo;Ramírez, Gustavo;Márquez, Eduardo;Pimentel, Lisa;Regino-Zamarripa, Nora E;Mendoza-Milla, Criselda;Goodina, Aminadab;Hernández-Montiel, Erika;Barquera, Rodrigo;Santibañez, Alfredo;Domínguez-Cherit, Guillermo;Pérez-Padilla, Rogelio;Regalado, Justino;Santillán-Doherty, Patricio;Salas-Hernández, Jorge;Zúñiga, Joaquín;
Journal International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Year 2019
DOI
S1201-9712(19)30355-8
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.