Network analysis of oyster transcriptome revealed a cascade of cellular responses during recovery after heat shock.

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ID: 35127
2012
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Abstract
Oysters, as a major group of marine bivalves, can tolerate a wide range of natural and anthropogenic stressors including heat stress. Recent studies have shown that oysters pretreated with heat shock can result in induced heat tolerance. A systematic study of cellular recovery from heat shock may provide insights into the mechanism of acquired thermal tolerance. In this study, we performed the first network analysis of oyster transcriptome by reanalyzing microarray data from a previous study. Network analysis revealed a cascade of cellular responses during oyster recovery after heat shock and identified responsive gene modules and key genes. Our study demonstrates the power of network analysis in a non-model organism with poor gene annotations, which can lead to new discoveries that go beyond the focus on individual genes.
Reference Key
zhang2012networkplos Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhang, Lingling;Hou, Rui;Su, Hailin;Hu, Xiaoli;Wang, Shi;Bao, Zhenmin;
Journal PloS one
Year 2012
DOI
DOI not found
URL
http://europepmc.org/articles/PMC3329459?pdf=render
Keywords Keywords not found

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