Terasaki spiral ramps and intracellular diffusion.

Clicks: 301
ID: 34430
2019
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Abstract
The sheet-like endoplasmic reticulum (ER) of eukaryotic cells has been found to be riddled with spiral dislocations, known as 'Terasaki ramps', in the vicinity of which the doubled bilayer membranes which make up ER sheets can be approximately modeled by helicoids. Here we analyze diffusion on a surface with locally helicoidal topological dislocations, and use the results to argue that the Terasaki ramps facilitate a highly efficient transport of water-soluble molecules within the lumen of the endoplasmic reticulum.
Reference Key
huber2019terasakiphysical Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Huber, Greg;Wilkinson, Michael;
Journal physical biology
Year 2019
DOI
10.1088/1478-3975/ab4080
URL
Keywords Keywords not found

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