AMPK/USP10 loop activation of ACE2 in pulmonary hypertension: extending the cardiovascular-kidney-metabolic continuum to the pulmonary circulation?

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ID: 338128
2026
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Abstract
The cardiovascular-kidney-metabolic continuum includes the pulmonary circulation, with AMPK/USP10 loop activation as a central hub (white box in the middle of the figure) for ACE2 stability and prevention of endothelial dysfunction.
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Authors Irene Marthe Lang, Thomas A. Zelniker
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Journal european heart journal
Year 2026
DOI
10.1093/eurheartj/ehag762
URL
https://academic.oup.com/eurheartj/advance-article-pdf/doi/10.1093/eurheartj/ehag762/72697229/ehag762.pdf
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