Multimodal imaging features of primary jaw lymphoma: a retrospective analysis of 53 cases

Clicks: 1
ID: 337907
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #53 of 55 articles by views in dentomaxillofacial radiology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
OBJECTIVES: This study systematically evaluated imaging characteristics of primary jaw lymphoma using multiple modalities to improve diagnostic accuracy and differentiation from other maxillofacial pathoses. METHODS: Fifty-three patients with histopathologically confirmed jaw lymphoma (January 2000-March 2025) were retrospectively reviewed. Clinical data including chief complaints and misdiagnosis history were investigated. Imaging features-lesion location, soft-tissue swelling, cortical destruction pattern, internal structure, and metabolic activity-were assessed using panoramic radiography, CT, MRI, and PET. RESULTS: Initial misdiagnoses as odontogenic infection or inflammation led to inappropriate treatments in 27 of 53 cases (50.9%). Lesions most commonly involved the maxillary tuberosity (24.5%), with maxillary sinus extension in 74.2% of maxillary cases. Prominent soft-tissue swelling was observed in 50.9%, while severe cortical destruction predominated (61.2%). CT evaluation revealed cortical micro-perforations in 48.9% of cases occurring exclusively within the maxilla-though predominant in only 16.3%. PET imaging commonly demonstrated multi-site involvement with intense FDG uptake comparable to brain activity. CONCLUSIONS: Primary jaw lymphoma demonstrated characteristic features including severe cortical destruction with micro-perforation and prominent soft-tissue swelling. Frequent cortical micro-perforations highlight the importance of careful CT evaluation for subtle cortical breakthrough. Recognition of these features, particularly with non-specific clinical symptoms, may improve early diagnostic suspicion, reduce misdiagnosis as odontogenic infection, and facilitate timely biopsy and management. ADVANCES IN KNOWLEDGE: This is the first study to systematically characterize cortical micro-perforation as a distinctive imaging feature of primary jaw lymphoma. This finding may help reduce misdiagnosis as an odontogenic infection.
Reference Key
openalex_W7224775893 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jyotsna Jaswanth, Kyung‐Hoe Huh, Gyu-Dong Jo, Jo-Eun Kim, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee
Journal dentomaxillofacial radiology
Year 2026
DOI
10.1093/dmfr/twag072
URL
https://academic.oup.com/dmfr/advance-article-pdf/doi/10.1093/dmfr/twag072/72616467/twag072.pdf
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.