Validation of the British Cardiovascular Intervention Society Jeopardy Score from coronary CT angiography in TAVI candidates

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ID: 337473
2026
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Ranked #70 of 72 articles by views in European Heart Journal - Imaging Methods and Practice

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Abstract
Abstract Aims Severe aortic stenosis and coronary artery disease (CAD) frequently coexist in patients undergoing transcatheter aortic valve implantation (TAVI). The British Cardiovascular Intervention Society Jeopardy Score (BCIS-JS) is a well established score for determining CAD extent and jeopardized myocardium. The aim of the present study was to validate a CT-derived BCIS-JS (CT-BCIS-JS) against invasive angiography–derived BCIS-JS (iBCIS-JS) in TAVI candidates. Methods and results A total of 108 patients (median age 84 yrs, 43% female) undergoing CCTA prior to TAVI were included. CT-BCIS-JS and iBCIS-JS were both calculated and compared to each other with Spearman rank correlation and Bland-Altman analysis. Diagnostic performance of CT-BCIS-JS for detecting extensive CAD (iBCIS-JS ≥6) was assessed using sensitivity, specificity, positive and negative predictive values, and agreement was evaluated using Cohen’s kappa (κ). Correlation between CT-BCIS-JS and iBCIS-JS was good (Spearman’s rho = 0.61). Bland-Altman analysis demonstrated systematic overestimation of BCIS-JS with CT (by an average of 2.2 units) with rather wide limits of agreement (-4.6 to 9.1). A CT-BCIS-JS ≥6 had excellent sensitivity and negative predictive value (93% and 99% respectively) to detect extensive CAD on invasive angiography, but moderate to low specificity and positive predictive value (76% and 39%, respectively), and agreement for dichotomized BCIS-JS was moderate (κ = 0.44). Conclusion CT-BCIS-JS may serve as a reliable rule-out tool for extensive CAD, potentially reducing the need for invasive angiography in selected TAVI candidates, although systematic overestimation limits its rule-in capability.
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Authors
Journal European Heart Journal - Imaging Methods and Practice
Year 2026
DOI
10.1093/ehjimp/qyag183
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