Embolic complications of cardiac myxoma: A systematic review and meta-analysis of frequency, clinical characteristics, anatomical distribution and outcomes in contemporary cohorts

Clicks: 8
ID: 333703
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #129 of 147 articles by views in Interdisciplinary CardioVascular and Thoracic Surgery

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 147 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Abstract
Abstract Objectives Cardiac myxomas are the most common benign primary cardiac tumours and embolise, causing stroke, acute coronary syndrome, limb ischaemia, and visceral infarction. Although previous reviews examined clinical features and embolic risk factors, the frequency, anatomical distribution, management, and outcomes of myxoma-related embolisation have not been comprehensively synthesised. Methods We searched MEDLINE, Embase, Scopus, CINAHL, the Cochrane Library, and PubMed from inception to February 2026 for observational studies reporting embolic complications of confirmed cardiac myxoma; small (≤10-patient) and pre-2000 case series were excluded. Random-effects meta-analyses of proportions estimated patient-level embolic prevalence and event-level anatomical distribution. Results Across 47 studies (4,964 patients), pooled embolic prevalence was 19.7% (95% CI 16.7–23.1; I²=75.4%, 95% CI 62.8-87.5). Cerebral events predominated (75.6%), followed by peripheral limb (17.0%). Pooled early mortality was 1.9% (95% CI 1.3–2.7). Villous morphology and high tumour mobility were more associated with embolisation than size. Recurrence was uncommon (crude rate 2.0%) and mainly in familial disease or Carney complex. Conclusion Embolism is common and predominantly cerebral. Villous surface and tumour mobility were more consistently associated with embolisation than size and may inform the urgency of resection. However, evidence is retrospective; the optimal timing after embolic presentation remains undefined, and prospective validation is required.
Reference Key
openalex_W7223390901 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors
Journal Interdisciplinary CardioVascular and Thoracic Surgery
Year 2026
DOI
10.1093/icvts/ivag288
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

No comments yet. Be the first to comment on this article.