Non-atrial/non-ventricular functional tricuspid valve regurgitation: a case report

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ID: 333530
2026
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Abstract
Abstract Background Functional tricuspid regurgitation (fTR) is usually caused by annular dilation and leaflet tethering secondary to right atrial (RA) or right ventricular (RV) remodeling. Rarely, extrinsic factors may impair annular motion. Case summary We report a 83-year-old woman with constrictive pericarditis who presented with right-sided heart failure and moderate tricuspid regurgitation. Multimodality imaging revealed a thickened pericardium, preserved RA and RV size, and a non-dilated, saddle-shaped annulus with markedly reduced motion. Following pericardiectomy, tricuspid annular mobility normalized, right-sided pressures decreased, and TR improved from moderate to mild. We introduce the term non-atrial/non-ventricular functional tricuspid regurgitation to describe this rare mechanism of isolated annular dysfunction caused by pericardial tethering. Discussion This case highlights a novel, distinct and reversible form of fTR caused by pericardial constraint rather than chamber remodeling. We propose the term non-atrial/non-ventricular fTR to describe this mechanism. Recognizing this entity may guide surgical decision-making and avoid unnecessary tricuspid valve intervention.
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Authors Netra Nambiar Veetil, Nicolas Merke, Maria Hajduzcenia, Volkmar Falk, Christoph Knosalla
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Journal European Heart Journal - Case Reports
Year 2026
DOI
10.1093/ehjcr/ytag753
URL
https://doi.org/10.1093/ehjcr/ytag753
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