Lung ultrasound in ambulatory adults with HFpEF: Association between pulmonary congestion and one-year outcomes

Clicks: 10
ID: 332584
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #70 of 80 articles by views in European Heart Journal Open

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Aims Early detection of congestion among adults with heart failure and preserved ejection fraction (HFpEF) is critical to optimize therapy prior to overt decompensation, yet traditional tools are insensitive. We sought to examine the association between B-lines on lung ultrasound (LUS) in ambulatory adults with HFpEF and relate these to one-year outcomes. Methods In a prospective, multi-site observational study, using a pocket ultrasound device, 8-zone LUS was performed in outpatients with HFpEF, left ventricular ejection fraction ≥45% and NYHA class II-IV. Ultrasound videos were analyzed centrally, blinded to clinical findings and adjudicated outcomes. Results Among 415 participants (mean age 74 years, 52% women, 51% with obesity, median N-terminal pro-B-type natriuretic peptide (NT-proBNP) 744 pg/ml) B-lines ranged from 0 to 36 (median 3 [interquartile range 1, 6]). A total of 108 events occurred during follow-up (89 HF events, 19 deaths). Participants in the highest B-line tertile (>5 B-lines) had a higher risk of total HF events and all-cause death (rate ratio 2.37 [95% CI 1.33, 4.25; P=0.004]) and a first HF event or death (HR 2.68 [95% CI 1.54, 4.64; P<0.001]) during one-year follow-up. These associations persisted after adjusting for age, sex, body mass index, diabetes, atrial fibrillation/flutter and NT-proBNP (first events only). Conclusions Among ambulatory adults with HFpEF, a higher number of B-lines at baseline identified those at increased risk of both total HF events and all-cause death, and first HF event or death independent of known risk markers. LUS is a scalable, non-invasive strategy to assess congestion and prognosis in adults with HFpEF.
Reference Key
openalex_W7222500901 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Elke Platz, Kirsty McDowell, Deepak K. Gupta, Brian Lee Claggett, Alice C. Brennan, Jonathan W. Cunningham, Debra Dixon, Kieran F. Docherty, Karola Jering, Rashundra Oggs, Andrew Perry, Madeleine Schwede, S. Sukumar, Jean W. Wassenaar, Eldrin Foster Lewis, John J.V. McMurray, Ross T. Campbell
Are you one of these authors? Claim your profile
Journal European Heart Journal Open
Year 2026
DOI
10.1093/ehjopen/oeag176
URL
https://doi.org/10.1093/ehjopen/oeag176
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.