Creating and Testing the Acceptability and Feasibility of a Novel Video-Based Smoking Cessation Intervention Tailored for Individuals with Cancer: Results for Alliance for Clinical Trials in Oncology Trial A21_Pilot 12

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2026
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Ranked #135 of 160 articles by views in nicotine & tobacco research : official journal of the society for research on nicotine and tobacco

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Abstract
Abstract Introduction Cigarette smoking poses unique risks for cancer survivors, but challenges remain with reach and efficacy of current interventions. The current randomized controlled pilot study created a video-based smoking cessation intervention for cancer survivors and tested acceptability/feasibility. Methods Participants were cancer survivors ages 21+ reporting current smoking, could read/understand English, and did not have medical/psychiatric conditions impairing ability to consent. Three videos were created and shown to survivors (N = 10) and refined based on feedback. Four additional videos were then created. Participants (N = 40) were randomized to a video (n=20, received 7 video links) or control (n=20, received link to NCI’s “Clearing the Air” online booklet) group. Primary outcomes were acceptability/feasibility, assessed using the Acceptability and Feasibility of Intervention measures (scores ≥4 considered acceptable/feasible). Secondary outcomes included quit attempts, abstinence, cigarettes per day, and cessation resource use. Surveys were completed at baseline and 1-week, 1-month, and-3 months post-randomization. Results Mean acceptability scores for video and control groups were 4.2 and 3.9, respectively. Mean feasibility scores for video and control groups were 4.0 and 3.8, respectively. Video participants saw decreases in cigarettes per day that were sustained from baseline (Mean [M]=16.2) through final follow-ups (M=7.7), and had numerically higher use of all nine cessation resources assessed. More video participants reported quit attempts at 1-week (55.0%), 1-month (50.0%), and 3-months (60.0%) than the control group (40.0% at 1-week and 1-month, 52.6% at 3-months). Conclusion The video intervention was acceptable/feasible among a diverse sample. Larger studies assessing intervention efficacy are needed.
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Authors Kinsey Pebley, Kathryn Moody, Amanda M. Palmer, Alana M. Rojewski
Journal nicotine & tobacco research : official journal of the society for research on nicotine and tobacco
Year 2026
DOI
10.1093/ntr/ntag220
URL
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