FP17.6 Acetabular dysplasia trajectories during growth from 6 to 18 years

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ID: 331219
2026
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Abstract
Abstract ICL17 - The Full Picture: Shaping the Future of Global Hip Preservation, Ground Floor Session Room (BMCC Level 0), October 9, 2026, 14:00 - 16:00 Introduction Acetabular dysplasia (AD) is an important risk factor for early onset of hip osteoarthritis (OA) in relatively young individuals. AD is defined using various hip morphology measures, but the course of these measures from childhood to adulthood remains unclear. This study aimed to describe the longitudinal course of certain validated AD measures and to identify distinct trajectories of these measures. Methods Data from the population-based Generation R Study were used. Participants were examined around age 6, 9, 13 and 18 years. Participants with high-resolution anteroposterior (AP) dual-energy x-ray absorptiometry (DXA) of the right hip and AP full-body DXA were included. Hip shape was outlined with radiological landmarks used to calculate the lateral center edge angle (LCEA; indicator of acetabular coverage), and the acetabular depth-width ratio (ADR; quantifying acetabular depth). The course of LCEA and ADR was assessed using all available data. Latent class growth analysis (LCGA) was used to identify trajectories, including participants with at least two measurements. Results In total, 6332 participants were included. Both LCEA and ADR increased from ages 6 to 18, reaching mean values of 29.9° (SD 5.8) for LCEA and 326.4 (SD 31.8) for ADR. Both measures generally leveled off around age 13, particularly in females. In the LCGA, 3868 participants were included. No significant trajectories were identified for LCEA. For ADR, a quadratic two-class model best fit the data in both sexes. In males, mean ADR at age 18 was 380.4 (SD 23.3) in subgroup 1 (n=199), and 317.0 (SD 26.0) for subgroup 2 (n=1728). In females, corresponding values were 353.4 (SD 20.5) in subgroup 1 (n=808), and 310.3 (SD 22.0) in subgroup 2 (n=1321). Conclusion This study describes the longitudinal course of the LCEA and ADR from childhood to early adulthood. While no distinct LCEA trajectories were observed, two ADR trajectories were identified in both sexes, mainly differing in acetabular depth at age 18. The smaller subgroups showed a deeper acetabulum during growth. Lower ADR values, indicating a shallower acetabulum, and are associated with AD. Understanding of acetabular development may support earlier identification of individuals at risk for AD-related hip OA.
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Authors Nadine Hendriks, Zhongcan Zheng, Fleur Boel, F Rivadeneira, Carl Johan Tiderius, Sita Bierma‐Zeinstra, Rintje Agricola, J. Runhaar
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Journal Journal of hip preservation surgery
Year 2026
DOI
10.1093/jhps/hnag043.134
URL
https://doi.org/10.1093/jhps/hnag043.134
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