Changes in Doravirine Pharmacokinetics During Pregnancy: A Longitudinal Single Dose Study

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ID: 329918
2026
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Abstract
Abstract Physiological changes during pregnancy may alter the pharmacokinetics of antiretrovirals, but pregnancy pharmacokinetic/dynamic data may lag years after drug approval. This single-dose approach allows for earlier data generation, estimating total and protein-unbound doravirine pharmacokinetics in women living with HIV during their second trimester, third trimester, and postpartum.
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openalex_W7214489588 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors
Journal The Journal of infectious diseases
Year 2026
DOI
10.1093/infdis/jiag484
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