Demographic, Clinical, and Mycologic Differences Between Invasive Fungal Sinusitis and Pneumonia in Hematologic Malignancy

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ID: 329767
2026
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Abstract
Abstract Among 132 patients with hematologic malignancies and invasive fungal disease, invasive fungal sinusitis was associated with greater dissemination, lower biomarker sensitivity, more diverse fungal pathogens, and higher rates of chronic rhinosinusitis and sinonasal defects than invasive fungal pneumonia. These findings suggest distinct clinical syndromes with different risk factors and diagnostic considerations.
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Authors Simran Gupta, Tejas S. Athni, Esther Arbona‐Haddad, Inia Pérez, Alexis D Liakos, Alexandra Tong, Maria Shehata, Carolyn Strauch, Muneerah M Aleissa, Alice Z. Maxfield, Regan W. Bergmark, Victor Kovac, Amy C Sherman
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Journal Open forum infectious diseases
Year 2026
DOI
10.1093/ofid/ofag613
URL
https://doi.org/10.1093/ofid/ofag613
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