Neuropsychological evaluation of children with brain tumors in Denmark, 2010–2020: a nationwide cohort study

Clicks: 13
ID: 329361
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #55 of 65 articles by views in Neuro-Oncology Practice

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Background Survivors of childhood central nervous system (CNS) tumors are at high risk of neurocognitive impairment, and international guidelines recommend routine neuropsychological evaluation (NE) during follow-up. However, little is known about how consistently these recommendations were implemented in Danish clinical practice. This study examined the occurrence of NE among children diagnosed with CNS tumors in Denmark. Methods In this nationwide retrospective cohort study, we identified all children aged 0─17 years diagnosed with CNS tumors in Denmark between 2010 and 2020 (N = 446) using the Danish Childhood Cancer Registry. Medical records were reviewed to determine whether patients had received an NE. Time to first evaluation was analyzed using Cox regression to examine associations with age, sex, and treatment center. Results Overall, 34.3% of patients received at least one NE during follow-up. Among patients alive two years after diagnosis, 28.8% had received an NE; this proportion increased to 36.4% among patients who were alive five years after diagnosis. Among children diagnosed before age seven, the likelihood of receiving an NE increased with age. The likelihood of evaluation also differed between treatment centers. Conclusions Despite international recommendations for routine neuropsychological follow-up, only a minority of children with CNS tumors in Denmark received an NE during the study period. These findings describe neuropsychological follow-up in Denmark from 2010 to 2020, prior to the implementation of more systematic national initiatives. They highlight an unmet need for systematic neuropsychological monitoring in pediatric neuro-oncology survivorship care.
Reference Key
openalex_W7213964820 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Barbara Johanne Thomas Nordhjem, Jonathan Kjær Grønbæk, Clara Emilie Bruun, Birthe Lykke Thomsen, Michael Thude Callesen, Louise Tram Henriksen, Kjeld Schmiegelow, René Mathiasen
Are you one of these authors? Claim your profile
Journal Neuro-Oncology Practice
Year 2026
DOI
10.1093/nop/npag074
URL
https://doi.org/10.1093/nop/npag074
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.