Case report: Aortic Root Thrombus Presenting with Syncope and Embolic Events

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ID: 329186
2026
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Abstract
Abstract Background Aortic root thrombus is a rare but potentially life-threatening condition, often associated with systemic embolization or obstruction of coronary arteries (myocardial infarction). The most common reason is a complication to left ventricular assist device (LVAD) implantation, but it may occur in the absence of LVAD, for instance in structural valve disease or pro-thrombotic disorders antiphospholipid syndrome, hemolytic diseases and myeloproliferative disease), making diagnosis challenging. Case Presentation We report the case of a 47-year-old man with a history of deep venous thrombosis who presented with syncope, anemia, and new-onset atrial fibrillation. Initial evaluation revealed elevated troponin, cerebral and splenic embolic lesions, and a mobile aortic root mass measuring 2.3 x 1.3 cm. Despite extensive work-up, no autoimmune or hematological disorder was identified. Surgical removal of the thrombus was performed. His postoperative course was complicated by pericardial tamponade requiring drainage but was otherwise favourable. He was discharged on long-term anticoagulation with preserved cardiac function. Conclusion Aortic root thrombus may present with systemic embolization in otherwise healthy individuals without identifiable thrombophilia. Early recognition and surgical intervention are essential when thrombus size, mobility, and embolic risk are high.
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Authors Ai Phi Thuy Ho, Eirik Tjønnfjord, Ole-Christian Walter Rutherford
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Journal European Heart Journal - Case Reports
Year 2026
DOI
10.1093/ehjcr/ytag715
URL
https://doi.org/10.1093/ehjcr/ytag715
Keywords Keywords not found

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