Outcome of primary mitral valve surgery in pediatric patients: Results from a bi-centric study

Clicks: 9
ID: 328562
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #123 of 147 articles by views in Interdisciplinary CardioVascular and Thoracic Surgery

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 147 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
OBJECTIVES: Due to heterogenous mitral valve(MV) disease expression, primary MV surgery in children might be challenging, entailing suboptimal results. METHODS: In this bi-centric collaboration all children undergoing primary MV surgery from 1987 to 2023 were included. Patients with atrioventricular septal defect and univentricular physiology were excluded. Study end-points were survival and need for MV reoperation and/or replacement, including multivariable risk factor analysis. RESULTS: Overall 109 patients underwent 158 procedures for predominantly mitral regurgitation(MR)(n = 82, 74.5%) and stenosis(MS)(n = 27, 25.5%), respectively at a median age of 5.7y(IQR 1.6-12) and 0.6y(IQR 0.3-1.2)(p < 0.001). Associated cardiac procedures were performed in 49(45.0%) patients. Primary repair was successful in 103(94.5%) patients, but required 10 early reinterventions(4 re-repair and 6 replacement). Overall 5-year survival was 83.2±4.0% without difference between MV phenotypes(p = 0.871). Risk factors for mortality were MV repair in the first year of life, associated intracardiac correction, and open chest or need for ECMO at completion of surgery. The cumulative incidence of MV reoperation and replacement at 5 years were respectively 27.0±4.7% and 16.5±4.0%, in disadvantage of MS phenotype. MV repair during infancy, MS phenotype, use of commissural or Alfieri-repair and the need for early MV re-repair were significant predictors for later MV reoperation or replacement. CONCLUSION: Although primary mitral valve surgery in children remains challenging, an acceptable repair is achievable in more than 90%. Whereas younger age at repair is a strong predictor of clinical outcome, repair durability is equally depending on the type of MV disease in disadvantage of the stenosis phenotype.
Reference Key
openalex_W7212253357 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Alain Poncelet, Jean Rubay, Gebrine El Khoury, Simon Van Bockstaele, Paulien Van Nuffel, Thomas Martens, Katrien François, Thierry Bové
Are you one of these authors? Claim your profile
Journal Interdisciplinary CardioVascular and Thoracic Surgery
Year 2026
DOI
10.1093/icvts/ivag250
URL
https://doi.org/10.1093/icvts/ivag250
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.