Loopcity: An R package for the detection of chromatin loop communities from Hi-C data

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ID: 328453
2026
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Abstract
Abstract Summary Chromatin loops identified from Hi-C data are often analyzed individually, but recent studies suggest that they are often organized into highly interconnected multi-loop communities, the biological meaning of which is still not fully understood. Here we describe loopcity, an R package that identifies multi-loop communities from Hi-C data via the construction and clustering of weighted interaction networks. Availability and Implementation Available on GitHub at https://github.com/sarmapar/loopcity (currently submitting to Bioconductor) Supplementary information Supplementary data are available at Bioinformatics Advances online.
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openalex_W7212381769 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Sarah M Parker, J P Flores, Douglas H. Phanstiel
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Journal Bioinformatics advances
Year 2026
DOI
10.1093/bioadv/vbag269
URL
https://doi.org/10.1093/bioadv/vbag269
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