Clinicopathologically supported photodistributed hyperpigmentation with associated nail changes during adagrasib therapy
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ID: 327669
2026
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Abstract
Adagrasib is a selective KRAS G12C inhibitor increasingly used in advanced malignancies and is associated with a range of cutaneous adverse effects. However, pigmentary changes remain rarely reported. We report a patient with recurrent KRAS G12C–mutant non–small cell lung cancer who developed photodistributed hyperpigmentation with associated nail matrix changes following adagrasib therapy.
| Reference Key |
openalex_W7208778466
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|---|---|
| Authors | Brian Nolan, David Murphy, Mary Bennett |
| Journal | clinical and experimental dermatology |
| Year | 2026 |
| DOI |
10.1093/ced/llag382
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| URL | |
| Keywords | Keywords not found |
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