QPL-Enabled HTSlib Library: Accelerating Sequence File Compression using Intel IAA
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ID: 326457
2026
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Abstract
Abstract Summary Sequence analysis workflows require the accessibility of large datasets, which require state-of-the-art compression tools. These compression tools, such as Samtools, often rely on HTSlib as a GZip implementation, but are still limited by throughput on time-intensive compression. QPL-HTSLib offers order of magnitude speedups for the compression and decompression of the SAM and BAM file formats commonly used in genomics workflows at the cost of a slightly larger compressed file, and is a drop-in replacement for HTSlib on Intel systems. Availability QPL-HTSLib is freely available on Github as an open-source software project. Supplementary information Supplementary data are available at Bioinformatics Advances online.
| Reference Key |
openalex_W7204230547
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| Authors | Benjamin Laflen, Zheyu Li, Maxwell Urbina, Tajana Rosing, Niema Moshiri |
| Journal | Bioinformatics advances |
| Year | 2026 |
| DOI |
10.1093/bioadv/vbag250
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| URL | |
| Keywords | Keywords not found |
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