Long-term outcomes after supravalvar aortic stenosis repair: Impact of residual haemodynamics on reintervention

Clicks: 1
ID: 325121
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #76 of 79 articles by views in Interdisciplinary CardioVascular and Thoracic Surgery

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Objective Surgical repair of supravalvar aortic stenosis (SVAS) provides excellent early outcomes; however, late reintervention remains common. The determinants of left ventricular outflow tract (LVOT) failure, particularly the role of residual haemodynamics, remain incompletely defined. We sought to identify predictors of LVOT reintervention in a contemporary cohort. Methods A retrospective study of consecutive patients aged <18 years undergoing SVAS repair between 2005 and 2024 was performed. Primary endpoints were overall survival and freedom from LVOT reintervention. Survival and freedom from reintervention were assessed using Kaplan–Meier analysis. Multivariable Cox regression was used to identify independent predictors of LVOT reintervention. Results Seventy-seven patients underwent repair at a median age of 3 (1–8) years, with median follow-up of 9.3 (6–14) years. There was no early or late mortality, nineteen patients (25%) required reintervention, including 16 (21%) LVOT-related procedures. Freedom from LVOT reintervention was 74% at 10 years and 71% at 15–20 years. Discharge LVOT velocity >3 m/s was independently associated with LVOT reintervention (HR 11.66, 95% CI 3.56–38.18; p < 0.001). Younger age was also independently associated with increased risk (HR per year 0.74, 95% CI 0.59–0.94; p = 0.013) for LVOT re-intervention. Coronary abnormalities were documented in 17% of patients, with one early coronary reintervention. Conclusion SVAS repair is associated with excellent long-term survival. Residual discharge velocity emerged as an independent predictor of late LVOT reintervention supporting the importance of achieving optimal haemodynamic relief at the index operation and structured lifelong surveillance.
Reference Key
openalex_W7203636465 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nabil Hussein, Branko Mimic, Mats Synnergren, Nagarajan Muthialu, Victor Tsang, Martin Kostolny
Journal Interdisciplinary CardioVascular and Thoracic Surgery
Year 2026
DOI
10.1093/icvts/ivag230
URL
https://doi.org/10.1093/icvts/ivag230
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.