Clinical Spectrum, Clinical Associations, and Treatment Outcomes of Scedosporiosis in South India: A Retrospective Cohort Study

Clicks: 37
ID: 324372
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #104 of 187 articles by views in medical mycology

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 187 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Scedosporium is an emerging opportunistic filamentous fungus widely distributed in soil and stagnant water. Mortality remains substantial and management is often challenging due to intrinsic antifungal resistance and delays in diagnosis. In this retrospective cohort study, we describe the clinical spectrum, microbiological characteristics, and outcomes of microbiologically culture-confirmed scedosporiosis at a tertiary care center in South India between May 2016 and August 2024. Eighteen patients were included, with a median age of 54 years and a predominance of male patients. Contrary to the patterns described in many Western and transplant-focused cohorts, the majority of infections in our series involved osteomyelitis and paranasal sinus disease. Disseminated infection was rare but was associated with poor outcomes. Voriconazole-based therapy was the most commonly used antifungal regimen, and surgical intervention was required in six cases. Our findings highlight a distinct clinical pattern of scedosporiosis in our setting, with osteomyelitis and sinusitis emerging as predominant presentations. These observations emphasize the importance of maintaining a high index of suspicion for Scedosporium infection in chronic bone and sinus disease, particularly when patients fail to respond to conventional antibacterial therapy.
Reference Key
openalex_W7201976771 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Malavika Krishnakumar, Gayathri Mohan, Apeksha Singh, Annup Balan, Georg Gutjahr, Merlin Moni, Dipu TS
Are you one of these authors? Claim your profile
Journal medical mycology
Year 2026
DOI
10.1093/mmy/myag074
URL
https://doi.org/10.1093/mmy/myag074
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.