Genetic variation in the long pentraxin PTX3 and Dectin-1 does not predispose to influenza- or COVID-19-associated pulmonary aspergillosis
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ID: 324271
2026
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Abstract
Abstract In this multicentric study, we found no association regarding incidence or outcome between common single nucleotide polymorphisms in PTX3 and CLEC7A and invasive pulmonary aspergillosis in patients with severe viral pneumonia. The distinct pathophysiology of virus-associated pulmonary aspergillosis warrants exploration of genetic variation in novel candidates.
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| Authors | Simon Feys, Jannes Heylen, Samuel M. Gonçalves, Inês Pereira, Cato Jacobs, Hanne Moon Lauwers, Hanne Beeckmans, Marc Bourgeois, Yves Debaveye, P. Depuydt, Pascal Frederiks, Greet Hermans, Martin Hoenigl, Lenn Maessen, Philippe Meersseman, Katrien Lagrou, Piet Lormans, Marijke Peetermans, Marick Starick, Karin Thevissen, Lore Vanderbeke, Robin Vos, Alexander Wilmer, Frank L. van de Veerdonk, Johan Van Weyenbergh, Sarah Sedik, Jürgen Prattes, Stella Wolfgruber, Augusto Vincent, Marius Huguet, Elena Elias, Angelina Thomas Villikudathil, Cristina Cunha, Joost Wauters, Agostinho Carvalho |
| Journal | The Journal of infectious diseases |
| Year | 2026 |
| DOI |
10.1093/infdis/jiag403
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| URL | |
| Keywords | Keywords not found |
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