An Exploratory Study of Host Plasma Proteomic Signatures that Distinguish Secondary and Early Latent Syphilis in Adults
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ID: 323670
2026
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Abstract
Abstract Syphilis diagnostics struggle to distinguish active from treated disease. Using tandem-mass-tag proteomics on plasma from 10 secondary and early latent syphilis cases and 8 matched controls, we identified 54 differentially regulated proteins categorized under several biological pathways. Those exploratory findings support proteomics as a tool for developing novel syphilis diagnostics.
| Reference Key |
openalex_W7172416221
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|---|---|
| Authors | Cody Chou, Shad R. Morton, Kelika A. Konda, Silver K. Vargas, Michael Reyes-Díaz, Francesca Rosalia De Maria Vasquez Vasquez, Carlos F. Cáceres, Jeffrey D. Klausner, Trey Toombs, Rushdy Ahmad, Lao‐Tzu Allan‐Blitz |
| Journal | Open forum infectious diseases |
| Year | 2026 |
| DOI |
10.1093/ofid/ofag498
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| URL | |
| Keywords | Keywords not found |
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