Clinical, molecular and immunological characteristics of scrub typhus in Nepal
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ID: 323221
2026
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Abstract
Abstract In a serologically diagnosed Nepalese scrub typhus cohort (n=77), gastrointestinal symptoms were common. We assessed Orientia tsutsugamushi DNA in serum and performed TSA56 genotyping. Orientia DNA was detected in 10/77 samples (12%). TSA56 sequencing identified four genotypes. PCR-positivity was associated with diarrhea, groin lymphadenopathy, and stronger Th1-type cytokine responses.
| Reference Key |
openalex_W7172138103
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|---|---|
| Authors | Anurag Adhikari, Carina Münch, Nora En-Nosse, Binod Rayamajhee, Gaurab Karki, Binod GC, Pardip Oli, Lea Fromm, Johanna Schwarz, Siddhesh Sapre, Jonas Mehl, Sagar Aryal, Dennis Tappe, Christian Keller |
| Journal | Open forum infectious diseases |
| Year | 2026 |
| DOI |
10.1093/ofid/ofag390
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| URL | |
| Keywords | Keywords not found |
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