A Destructive Midline Facial Lesion: An Elusive Diagnosis

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ID: 323211
2026
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Ranked #124 of 245 articles by views in clinical and experimental dermatology

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Abstract
Extranodal NK/T-cell lymphoma is a highly aggressive EBV-driven lymphoma that can masquerade as benign inflammatory or infective midline lesions, often leading to delayed diagnosis. Extensive necrosis and angio-destructive growth may render biopsies inconclusive; repeat deep biopsy with immunohistochemistry and EBER testing is often required to establish diagnosis and avoid misinterpretation. Early recognition is critical, outcomes depend on prompt initiation of asparaginase-based regimens with radiotherapy.
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openalex_W7172102423 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shivangi Singh, Ananya Arya, Saikat Mitra, Gitesh U. Sawatkar
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Journal clinical and experimental dermatology
Year 2026
DOI
10.1093/ced/llag343
URL
https://doi.org/10.1093/ced/llag343
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