A Destructive Midline Facial Lesion: An Elusive Diagnosis

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ID: 323211
2026
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Ranked #62 of 169 articles by views in clinical and experimental dermatology

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Abstract
Extranodal NK/T-cell lymphoma is a highly aggressive EBV-driven lymphoma that can masquerade as benign inflammatory or infective midline lesions, often leading to delayed diagnosis. Extensive necrosis and angio-destructive growth may render biopsies inconclusive; repeat deep biopsy with immunohistochemistry and EBER testing is often required to establish diagnosis and avoid misinterpretation. Early recognition is critical, outcomes depend on prompt initiation of asparaginase-based regimens with radiotherapy.
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openalex_W7172102423 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shivangi Singh, Ananya Arya, Saikat Mitra, Gitesh U. Sawatkar
Journal clinical and experimental dermatology
Year 2026
DOI
10.1093/ced/llag343
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