A case report of pacemaker endocarditis presenting as osteitis in a high surgical risk patient: A management challenge with thromboaspiration and leadless pacemaker implantation

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ID: 322971
2026
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Abstract
Abstract Background Cardiac implantable electronic device-related infective endocarditis is a serious and increasingly frequent complication, often presenting atypically in frail patients with multiple comorbidities. Case Summary We report the case of an 83-year-old man admitted with fever and heel pain, who developed heart failure symptoms. Investigations revealed Staphylococcus aureus bacteremia, osteitis, spondylodiscitis, and a large tricuspid valve vegetation (26 mm) attached to the pacemaker lead, complicated by pulmonary embolism. Given his high surgical risk and resistant Gram-positive bacteremia, a multidisciplinary endocarditis team opted for percutaneous vegetation thromboaspiration, complete device extraction, and pacing was ensured via an externalized temporary-permanent pacing system. After infection clearance, a leadless pacemaker was successfully implanted. The clinical outcome was favorable, with no recurrence or complications on follow-up. Conclusion This case emphasizes the importance of early suspicion, advanced imaging, and tailored management of CIED-related endocarditis. Leadless pacemakers and percutaneous aspiration represent valuable strategies in high-risk patients to reduce infection recurrence and embolic risk.
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openalex_W7171775878 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Wassim Beladel, Zakaria Chaib, Caroline Birgy, Isabelle Lecardonnel, Mohamed El Minaoui
Journal European Heart Journal - Case Reports
Year 2026
DOI
10.1093/ehjcr/ytag576
URL
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