Parallel Declines in HPV6/11-Related Disease Incidences: A National Study of Anogenital Warts and Recurrent Respiratory Papillomatosis in Norway
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ID: 322927
2026
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Abstract
Abstract Anogenital Warts (AGW) and Recurrent Respiratory Papillomatosis (RRP) are conditions caused by Human Papillomavirus (HPV) types 6/11 that can be prevented by vaccination. We analyzed Norwegian national registry data (2010-2023) to assess the impact of the 4-valent HPV vaccine introduced in 2009. AGW incidence among females aged 15-29 decreased significantly from 1,120.0 to 280.6 per 100,000 (APC: -10.3%), paralleling a sharp decline in RRP from 3.7 to 0.6 per 100,000 (APC: -11.3%). These results strongly support vaccination impact in reducing the burden of HPV 6/11-related diseases, suggesting successful interruption of transmission pathways and substantial population-level protection.
| Reference Key |
openalex_W7171673644
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| Authors | Madleen Orumaa, Ståle Nygård, Joseph Tota, Parag Mahale, Thea E. Hetland Falkenthal |
| Journal | Open forum infectious diseases |
| Year | 2026 |
| DOI |
10.1093/ofid/ofag456
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| URL | |
| Keywords | Keywords not found |
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