Utility of p53 Immunohistochemistry in Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma: A Retrospective Study of 50 Cases
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ID: 322476
2026
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Abstract
p53 immunohistochemistry shows a high frequency of aberrant expression in atypical fibroxanthoma and pleomorphic dermal sarcoma, reflecting underlying UV-associated TP53 alterations. While not specific, p53 serves as a useful adjunct in challenging cases, particularly in distinguishing residual tumour from reactive changes.
| Reference Key |
openalex_W7170133157
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|---|---|
| Authors | Ghadah Al-Sharbatee, Maged Daruish, Daniella Wu, Saleem Taibjee |
| Journal | clinical and experimental dermatology |
| Year | 2026 |
| DOI |
10.1093/ced/llag320
|
| URL | |
| Keywords | Keywords not found |
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