Comparative genomics of herpes simplex virus 2 isolated from a maternal-neonatal dyad reveals high consensus sequence homology as well as minor variant diversity

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ID: 322366
2026
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Abstract
Abstract Neonatal herpes simplex virus disease most often occurs following mother-to-neonate transmission during childbirth. However, genomic differences between the maternal and neonatal viral populations are poorly understood. Here, we performed deep whole-genome sequencing of clinical HSV-2 samples obtained from a maternal-neonatal dyad to investigate viral population dynamics during transmission.
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Authors Reem Abu Rass, Lacy M. Simons, Christopher D. Bowen, Haley S Carter, Daniel W. Renner, Moriah L Szpara, Lisa N. Akhtar
Journal journal of the pediatric infectious diseases society
Year 2026
DOI
10.1093/jpids/piag064
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