“Deep Learning-Based Detection of Pediatric Brain Tumor Presence on MRI”

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ID: 322256
2026
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Ranked #69 of 103 articles by views in Neuro-Oncology Advances

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Abstract
Abstract Introduction Pediatric cancer imposes a significant global burden, with ∼400,000 new cases annually [WHO, 2025]. Magnetic resonance imaging (MRI) is a fundamental technique for timely diagnosis; however, interpretation can be subjective. In this context, convolutional neural networks (CNNs) have emerged as a promising tool for early and accurate detection of brain tumors in pediatric patients. Objective To develop and validate a CNN model for tumor detection tasks (tumor vs. non-tumor) of pediatric brain MRI images using T1-weighted imaging. Methodology T1-weighted brain MRI images from 285 pediatric patients were included (140 with confirmed tumors and 145 controls). A CNN architecture with convolutional layers, max-pooling, and dropout regularization was implemented. The model was trained and evaluated using cross-validation, employing the following metrics: accuracy, precision, recall, and F1-score. Model performance was compared across training configurations of 10–50 and 100 epochs to determine the optimal setup. Results The model trained for 40 epochs achieved the best overall performance, with a precision of 99%, a recall of 100%, and an F1-score of 99%. These metrics demonstrate excellent tumor detection while eliminating false negatives, a crucial aspect in pediatric oncology. Conclusion The CNN demonstrates strong potential as a diagnostic aid for detection brain tumors using pediatric MRI images. Its integration into clinical environments could contribute to more objective interpretation, optimize diagnostic workflows, and provide imaging follow-up before and after treatment.
Reference Key
openalex_W7170734967 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Estefania Reyes Soto, Silvia Hidalgo Tobón, Dulce Judith Almanza Aranda, Bertha Lilia Romero Baizabal, Benito de Celis Alonso, Samuel Torres García, Jorge Villalpando Espinoza
Journal Neuro-Oncology Advances
Year 2026
DOI
10.1093/noajnl/vdag187
URL
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