Regulatory whiplash in dermatology: estimating the hidden cost of isotretinoin guidance reversal

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ID: 321867
2026
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Abstract
This article estimates the hidden operational and financial cost of repeated isotretinoin regulatory change across UK dermatology services following the MHRAs 2023 and 2026 guidance cycles. Using transparent, conservative assumptions, it argues that substantial clinical, governance, and organisational resource was diverted from patient care and that future regulatory interventions should be evaluated not only for safety intent, but also for implementation burden and opportunity cost.
Reference Key
openalex_W7170046856 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors James Denny
Journal clinical and experimental dermatology
Year 2026
DOI
10.1093/ced/llag316
URL
Keywords Keywords not found

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