Shifting Burden of Childhood Cancer Mortality in the United States: Progress and Persistent Inequities
Clicks: 6
ID: 321584
2026
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
0.0
/100
6 views
0 readers
AI Quality Assessment
Not analyzed
Readership in this journal
Ranked #48 of 302 articles by views in american journal of epidemiology
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 302 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
While 5-year survival following childhood cancer rose greatly from ~60% in the mid-1970s to 85% today, inequities persist and conventional survival metrics obscure the true burden and shifting distribution of deaths. To address this, we used Surveillance, Epidemiology, and End Results registries to evaluate excess mortality rates and counts (AER and AEC), new metrics quantifying mortality attributable to childhood cancer, among 47,545 U.S. children diagnosed before age 20 during 1975-2014, with follow-up through 2018. We quantified trends across subgroups and assessed modification by county-level income and rurality. AER declined across groups but at different magnitudes. From 1975-79 to 2010-14, declines were 75% in non-Hispanic White (NHW), 62% in non-Hispanic Black, and ~63% in Hispanic and Asian/Pacific Islander children. Among non-Hispanic American Indian/Alaska Native children, AER fell briefly with no clear improvement subsequently. Absolute burden shifted: AEC fell among NHW (8,874 in 1990-94 to 5,134 in 2010-14) but rose among other subgroups (4,826 to 5,213). By 2010-14, non-NHW children accounted for more deaths despite >15,000 fewer diagnoses than NHW children. These findings show a shifting national burden: despite overall survival gains, persistent and sometimes worsening inequities mean deaths are increasingly concentrated among non-NHW subgroups.
| Reference Key |
openalex_W7169671156
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | Jessica L. Baedke, Qi Liu, Shizue Izumi, Tomoko Yoshida, N. Lamichhane, Sahar Aliabadi, José Miguel Martı́nez, I‐Chan Huang, Armstrong Gt, Yutaka Yasui |
| Journal | american journal of epidemiology |
| Year | 2026 |
| DOI |
10.1093/aje/kwag169
|
| URL | |
| Keywords | Keywords not found |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.