SlWRKY6 Mediates H2S Signaling and SlGRF1-SlGIF2 Module to Coordinately Regulate Plant Growth, Fruit yield and Ripening in Tomato

Clicks: 1
ID: 321131
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #491 of 502 articles by views in Plant physiology and biochemistry : PPB

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 502 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Hydrogen sulfide (H2S), a gaseous signaling molecule, retards plant senescence and fruit ripening via protein persulfidation. However, the molecular mechanism underlying its coordination of fruit ripening with plant growth and development remains undefined. This study found that H2S could delay tomato fruit ripening and leaf senescence, and H2S defective mutant sllcd1 shows premature fruit ripening and stunted growth. Overexpression of SlWRKY6, which could be persulfidated by H2S, promotes fruit ripening and reduces fruit number. Molecular assays demonstrated that SlWRKY6 directly binds to the promoter of SlGIF2, a transcriptional co-activator, to repress its expression. Notably, H2S attenuates the repressive effect through persulfidation of SlWRKY6 to increase SlGIF2 transcription. Furthermore, SlGIF2 physically interacts with the GROWTH-REGULATING FACTOR 1 (SlGRF1). Functional validation showed that SlGRF1-SlGIF2 complex serves as a positive regulator of tomato plant growth and fruit yield while concomitantly delaying fruit ripening. Conversely, slgrf1 gene-edited mutants exhibit reduced plant growth, fruit yield and accelerated ripening. Mechanistically, SlGRF1-SlGIF2 complex synergistically activates two downstream target genes: SlCYCD3;1, a key cell-cycle regulator required for cell proliferation and plant growth, and SlCBSX5, which encodes an H2S biosynthesis enzyme that retards fruit ripening. This study provides a module that SlWRKY6-SlGRF1-SlGIF2 integrates H2S signal and genetically coordinates plant growth, fruit yield and fruit ripening in tomato.
Reference Key
openalex_W7168406615 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Min Zhang, Lisheng Guan, Hongye Sun, Mengran Li, Xiaoyan Guo, Zixu Lu, Nannan Liu, Gaifang Yao, Hua Zhang, Kangdi Hu
Journal Plant physiology and biochemistry : PPB
Year 2026
DOI
10.1093/plphys/kiag512
URL
https://doi.org/10.1093/plphys/kiag512
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.