Comment on ‘An open-label phase II study of bitopertin in adults and adolescents with erythropoietic protoporphyria or X-linked protoporphyria’

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ID: 321035
2026
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Abstract
We read with interest the phase II BEACON study by Ross et al. on biopterin for erythropoietic protoporphyria (EPP). While the observed PPIX reductions are encouraging, several unaddressed methodological issues undermine the validity of the efficacy conclusions.
Reference Key
openalex_W7168236008 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhenzhen Xiao, Rui Li, Yingjian Tan
Journal clinical and experimental dermatology
Year 2026
DOI
10.1093/ced/llag299
URL
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